Start with the run you want to make.

Guides

Follow the signal.
Choose the next page.

Every page in this manual starts from a decision you actually face mid-run — which weapon line to commit to, how a sealed wall opens, what to inscribe before the final boss.

Sephiria rewards planning more than reflexes: inventory space is tight, upgrade branches are permanent within a run, and a failed loop reset costs you the loot that made the build work. The four pages below cover that arc end to end. The wiki orients you in the systems, builds turns weapon choices into a repeatable plan, secret rooms maps the exploration payoffs, and Destiny Inscription covers the long-term progression that carries across runs. Each page leads with the answer, then shows the sources and patch version behind it — so you can act on the advice, or check where it came from.

• First run or returning after 1.0? Open the wiki hub and orient yourself before committing to a build.
• Dying in the same chapter every time? The builds page reframes the problem as an equipment decision.
• Playing co-op? Skim secret rooms first — exploration payoffs are shared with the whole squad.